Immune cell-Cancer organoid co-culture platform
To reflect the patient's complex immune environment, we co-cultured tumor organoids with immune cells to replicate the tumor microenvironment
Endothelial cells or CAFs-Immune cell-Cancer organoid triple co-culture platform
We are developing an innovative platform that reflects the tumor microenvironment by establishing a triple co-culture system, which is composed of patient-derived organoids, iuumne cells, and either endothealial cells or cancer-associated fibroblasts (CAFs)
PODO Therapeutics utilizes cancer organoid culture technology, which replicates the unique characteristics of each patient's cancer tissue in terms of function, structure, and cellular composition, to achieve personalized treatment
Optimization of organoid culture for each cancer type
PODO Therapeutics has developed a protocol to optimize organoid culture for each type of cancer through experiments conducted under various condicitions, achieving a high success rate in organoid culture
Lung cancer organoid
Colorectal cancer organoid
Gastric cancer organoid
Example of organoid culture media optimization experiment
Medium composition 01
Medium composition 02
Select the best medium composition for culturing organoids
Medium composition 03
Medium composition 04
Analysis of gene mutations in organoids derived from cancer patients through sequencing
Gastric cancer organoid – H&E stain
Gastric cancer organoid – IHC (Claudin 18.2)
Lung cancer organoid – IHC (PD-L1)
Lung cancer organoid – IHC (EPCAM)